STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bcop_2442InterPro IPR001440:IPR011716:IPR019734; KEGG: bth:BT_2663 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR-1; Tetratricopeptide TPR-3; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide repeat family protein; IMG reference gene:2504108174. (545 aa)    
Predicted Functional Partners:
Bcop_2443
COGs: COG0226 ABC-type phosphate transport system periplasmic component; KEGG: bth:BT_2664 putative phosphate ABC transporter, phosphate-binding component; SPTR: Putative Phosphate-binding protein; IMG reference gene:2504108175.
 
     0.901
Bcop_2445
Biopolymer transport protein ExbD/TolR; InterPro IPR003400; KEGG: bvu:BVU_1617 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Putative uncharacterized protein; IMG reference gene:2504108177; PFAM: Biopolymer transport protein ExbD/TolR.
 
 
   0.837
Bcop_2444
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
   0.833
Bcop_2446
InterPro IPR003400; KEGG: bfs:BF3946 hypothetical protein; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Putative uncharacterized protein; IMG reference gene:2504108178; PFAM: Biopolymer transport protein ExbD/TolR.
 
 
   0.833
Bcop_2447
MotA/TolQ/ExbB proton channel; COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: bvu:BVU_1615 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family protein; manually curated; IMG reference gene:2504108179; PFAM: MotA/TolQ/ExbB proton channel family.
 
     0.771
Bcop_2433
Proton-translocating NADH-quinone oxidoreductase, chain M; COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227:IPR001750; KEGG: bth:BT_4059 NADH dehydrogenase I, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Putative uncharacterized protein; TIGRFAM: NADH-quinone oxidoreductase, chain M/4; IMG reference gene:2504108165; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
 
 
 
 0.698
Bcop_2439
NADH-ubiquinone oxidoreductase chain 49kDa; COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001268:IPR001135; KEGG: bvu:BVU_1757 NADH dehydrogenase I, chain D; PFAM: NADH-quinone oxidoreductase, subunit D; NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: Putative uncharacterized protein; IMG reference gene:2504108171; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
  
  
 0.618
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
    
  0.608
Bcop_1426
COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR012947; KEGG: bfr:BF2624 alanyl-tRNA synthetase; PFAM: Threonyl/alanyl tRNA synthetase, SAD; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Putative alanyl-tRNA synthetase; IMG reference gene:2504107135; PFAM: Threonyl and Alanyl tRNA synthetase second additional domain.
    
  0.608
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.607
Your Current Organism:
Bacteroides coprosuis
NCBI taxonomy Id: 679937
Other names: B. coprosuis DSM 18011, Bacteroides coprosuis DSM 18011, Bacteroides coprosuis PC139, Bacteroides coprosuis str. DSM 18011, Bacteroides coprosuis strain DSM 18011
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