Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
SCAB_0751Putative AMP-binding protein; PMID:10930733; PMID:11048953; domain prediction suggests cds may be fragment of secondary metabolism biosynthesis cluster see also SCAB0731, SCAB0721; Belongs to the ATP-dependent AMP-binding enzyme family. (540 aa)    
Predicted Functional Partners:
SCAB_0731
Putative phosphopantetheinyl transferase; PMID:11390684; domain prediction suggests cds may be fragment of secondary metabolism biosynthesis cluster see also SCAB0721, SCAB0751; Belongs to the P-Pant transferase superfamily.
 
 
 0.932
CBG73310.1
Putative type I polyketide synthase component; PMID:15217615.
  
 0.922
CBG73306.1
Putative type I polyketide synthase component; PMID:16208464; PMID:15870461.
  
 0.890
SCAB_0741
Hypothetical protein; No significant db matches.
 
    0.887
SCAB_0761
Putative oxidoreductase.
       0.823
CBG74860.1
Putative polyketide synthase.
  
 0.801
CBG75343.1
Putative type I polyketide synthase; PMID:16207901; PMID:16079135; PMID:11358695.
  
 0.790
SCAB_0721
Putative oxidoreductase; PF00441 and PF08028 fatty acid oxidation; may suggest role in secondary metabolite synthesis for instance PMID: 15942003.
 
     0.745
SCAB_3281
Putative NRPS-associated AMP-binding protein; PMID:15870461; PMID:16208464; PMID:15113000.
   
0.717
SCAB_1531
Putative adenylation protein; PMID:15113000; PMID:15870461; PMID:16208464; may be related to gene cluster SCAB1381-SCAB1481.
   
0.714
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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