close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCAB_0771Putative aminotransferase; PMID:15128576; related to ectoine biosynthesis aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)    
Predicted Functional Partners:
ectA
Putative L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
  
 0.986
desA
Putative siderophore biosynthesis pyridoxal-dependent decarboxylase DesA; PMID: 15600304; PMID:11274118; proposed reaction L-lysine <=> cadaverine +CO2.
 
 0.921
CBG73876.1
Putative amino acid decarboxylase.
 
 0.921
asd1
Putative aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
 0.907
asd1-2
Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
    
 0.907
thrA
Homoserine dehydrogenase.
     
 0.905
SCAB_3841
Putative homoserine dehydrogenase.
     
 0.905
ectD
Putative ectoine hydroxylase; Compatible solute ectoine: osmoprotectant.
 
  
 0.896
ectC
Putative L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
 
   
 0.803
SCAB_0751
Putative AMP-binding protein; PMID:10930733; PMID:11048953; domain prediction suggests cds may be fragment of secondary metabolism biosynthesis cluster see also SCAB0731, SCAB0721; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.618
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: medium (66%) [HD]