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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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CBG68793.1Putative TPP-requiring enzyme; Belongs to the TPP enzyme family. (561 aa)    
Predicted Functional Partners:
frc
Putative transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
 
 
 0.975
CBG68795.1
Conserved hypothetical protein.
 
 
 
 0.960
ilvN
Acetolactate synthase small subunit.
 
 
 0.940
ilvC
Acetolactate synthase small subunit; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.918
CBG68796.1
Putative transmembrane transport protein.
 
   
 0.906
CBG68790.1
Putative dehydrogenase.
 
 
 0.833
sucC-2
Succinyl-coa synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.778
SCAB_8031
Putative threonine dehydratase.
 
 0.703
ilvD
Dihydroxy acid/phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.689
CBG74038.1
Putative dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.687
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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