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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
SCAB_2121Putative membrane protein; No significant db matches. (209 aa)    
Predicted Functional Partners:
SCAB_2131
Putative substrate-CoA ligase.
     
 0.732
hcaB
2,3-dihydroxy-2,3-dihydrophenylpropionatedehydr og enase; Annotation transferred from E. coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.721
bphD
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD; Annotation transferred, perhaps biphenyl catabolism cf PMID: 2160220.
  
    0.711
hcaF
3-phenylpropionate dioxygenase, beta subunit; This operon in E. coli encodes a pathway for catabolism of aromatic acids; annotation transferred from E. coli.
       0.517
mhpB
2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
       0.454
SCAB_2111
Putative alcohol dehydrogenase.
       0.454
mhpD
2-keto-4-pentenoate hydratase; Annotation transferred from E. coli perhaps breakdown of aromatics cf PMID:9492273.
       0.452
mhpE
4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
       0.446
bphG
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.446
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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