Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SCAB_2131Putative substrate-CoA ligase. (530 aa)    
Predicted Functional Partners:
CBG74925.1
Putative polyketide synthase.
  
 0.934
CBG75341.1
Putative type I polyketide synthase.
  
 0.934
CBG74926.1
Putative polyketide synthase; PMID:16207901; PMID:11358695; PMID:9860992; PMID:14736915; many more matches.
  
 0.918
CBG75339.1
Putative type I polyketide synthase; PMID:16207901; PMID:16085885; PMID:11094342; PMID:14652074; PMID:10873841; PMID:16806745; TTA-Leu codon(s) 962 may indicate regulation by BldA.
  
 0.918
CBG75340.1
Putative type I polyketide synthase.
  
 0.918
CBG71460.1
Putative polyketide synthase; PMID:14652074; PMID:10767533; many ~30% similar.
  
 0.889
CBG75342.1
Putative type I polyketide synthase.
  
 0.881
CBG75343.1
Putative type I polyketide synthase; PMID:16207901; PMID:16079135; PMID:11358695.
  
 0.880
CBG75338.1
Putative type I polyketide synthase; PMID: 16207901; PMID:12770825; PMID:15561847.
  
 0.854
hcaB
2,3-dihydroxy-2,3-dihydrophenylpropionatedehydr og enase; Annotation transferred from E. coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
   0.792
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: medium (44%) [HD]