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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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hcaE3-phenylpropionate dioxygenase, alpha subunit; Annotation transferred from E. coli, perhaps 3-phenylpropionic acid breakdown cf PMID: 9603882. (441 aa)    
Predicted Functional Partners:
hcaF
3-phenylpropionate dioxygenase, beta subunit; This operon in E. coli encodes a pathway for catabolism of aromatic acids; annotation transferred from E. coli.
 
 
 0.986
hcaB
2,3-dihydroxy-2,3-dihydrophenylpropionatedehydr og enase; Annotation transferred from E. coli; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.981
hcaC
Ferredoxin subunit of phenylpropionate dioxygenase; Annotation transferred from E. coli.
 
  
 0.898
SCAB_2171
Putative aromatic hydrocarbons catabolism-related reductase.
 
     0.866
mhpB
2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
   
 0.782
bphD
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD; Annotation transferred, perhaps biphenyl catabolism cf PMID: 2160220.
 
 
   0.599
CBG68675.1
Iron-sulfur oxidoreductase beta subunit.
 
  
 0.553
mhpD
2-keto-4-pentenoate hydratase; Annotation transferred from E. coli perhaps breakdown of aromatics cf PMID:9492273.
 
   
 0.530
mhpE
4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
    0.499
bphG
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
   
 0.492
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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