Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ddlAD-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (385 aa)    
Predicted Functional Partners:
murF
putativeUDP-N-acetylmuramoyl-tripeptide--D-alan yl-D-alanineligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 0.995
alr
Putative alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
 
 0.984
murC
UDP-N-acetylmuramate--l-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.978
murD
Putative UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 0.974
murG
Putativeundecaprenyldiphospho-muramoylpentapept id eb-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.916
ftsQ
Cell division protein; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily.
  
  
 0.888
murB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.879
fstW
Putative cell division protein; PMID:8752351; Belongs to the SEDS family.
 
  
 0.869
murE
putativeUDP-N-acetylmuramoyl-L-alanyl-D-glutama te--2,6-diaminopimelateligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.827
gpdA
Glycerol-3-phosphate dehydrogenase; Cluster 0583 with SCAB79801; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
     
 0.818
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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