Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SCAB_2841Putative secreted protein. (369 aa)    
Predicted Functional Partners:
SCAB_2851
Putative integral membrane protein.
 
 
 0.964
CBG74144.1
Putative integral membrane protein.
 
 
 0.829
ftsH
Putative membrane-bound FtsH-family protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.782
arc
AAA ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 
 0.538
CBG72622.1
Conserved hypothetical protein; PMID:15215596; Belongs to the UPF0301 (AlgH) family.
  
    0.531
SCAB_5571
Conserved hypothetical protein.
  
  
 0.511
ctaC
Putative cytochrome c oxidase subunit II.
   
 
 0.495
CBG69651.1
Conserved hypothetical protein.
  
    0.476
CBG70448.1
Conserved hypothetical protein.
   
    0.464
SCAB_2831
Putative integral membrane protein.
       0.442
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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