Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBG70455.1Conserved hypothetical protein; PMID: 7500951; PMID: 10681332. (225 aa)    
Predicted Functional Partners:
fumC
Fumarate hydratase C; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.747
CBG73988.1
Conserved hypothetical protein.
  
     0.593
CBG70993.1
Putative membrane protein.
  
     0.570
CBG74097.1
Putative membrane protein.
  
     0.570
CBG70451.1
Conserved hypothetical protein.
       0.526
fumB
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.526
CBG70456.1
Conserved hypothetical protein; PMID: 1173148; PMID: 8885273.
       0.526
SCAB_58191
Pseudogene; Missing stop codon.
       0.526
wblI
Conserved hypothetical protein WblI; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
       0.525
CBG74963.1
Putative integral membrane protein.
  
     0.497
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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