Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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pckGPutative phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (611 aa)    
Predicted Functional Partners:
CBG70842.1
Putative oxidoreductase; PMID: 15328113.
   
 
 0.964
CBG73321.1
Putative thiamine-pyrophosphate-binding oxidoreductase alpha subunit; PMID:15328113.
   
 
 0.964
CBG75142.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.954
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
 
  
 0.951
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.948
citA
Citrate synthase; PMID:11325948; see also SCAB51341 putative citrate synthase; Belongs to the citrate synthase family.
   
 
 0.946
CBG72176.1
Putative citrate synthase; See also SCAB58791 citA; Belongs to the citrate synthase family.
   
 
 0.943
pyk2
Putative pyruvate kinase; Cluster 0606 with SCAB68861; Belongs to the pyruvate kinase family.
  
 
 0.942
pyk1
Putative pyruvate kinase; Cluster 0606 with SCAB28241; Belongs to the pyruvate kinase family.
  
 
 0.942
CBG68235.1
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.922
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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