Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBG70605.1Putative GTPase. (743 aa)    
Predicted Functional Partners:
CBG70604.1
Putative leucine-rich repeat protein; TTA-Leu codon(s) 58 may indicate regulation by BldA.
     0.951
guaB
IMP dehydrogenase/ GMP reductase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.894
CBG69749.1
Putative heat shock protein (hsp90-family).
  
 0.780
pgk
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 
 0.698
CBG69237.1
Putative helicase SNF2 family protein; Cluster 0487 with SCAB65921.
   
 0.679
CBG73592.1
Putative helicase SNF2 family protein; Cluster 0487 with SCAB21231.
   
 0.679
CBG69035.1
Conserved hypothetical protein.
 
 0.675
cya
Adenylate cyclase; PMID: 10376832.
   
 0.671
gmk
Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
 0.656
CBG75413.1
Putative thioredoxin reductase.
   
 0.643
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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