Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CBG70845.1Conserved hypothetical protein. (284 aa)    
Predicted Functional Partners:
CBG68821.1
Putative respiratory chain oxidoreductase; TTA-Leu codon(s) 59 may indicate regulation by BldA.
   
 0.978
SCAB_4821
Conserved hypothetical protein.
  
  
 
0.926
SCAB_4321
Conserved hypothetical protein.
  
  
 
0.924
CBG72290.1
Putative NAD(P)H dehydrogenase.
  
 
  0.903
CBG68381.1
Putative flavodoxin-like protein; Belongs to the WrbA family.
    
  0.900
menG
Putative methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
     
  0.900
CBG71460.1
Putative polyketide synthase; PMID:14652074; PMID:10767533; many ~30% similar.
  
 0.820
CBG70844.1
Putative transcriptional regulator.
 
     0.757
CBG70836.1
Putative dehydrogenase.
   
 0.739
nuoC
NuoC, NADH dehydrogenase subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
   
 0.739
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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