Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sppAPutative polyketide beta-ketoacyl synthase 1; PMID:12323376; PMID:15365693; PMID: 8344517; PMID:11959542; spore pigment; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (418 aa)    
Predicted Functional Partners:
sppB
Putative polyketide beta-ketoacyl synthase 2; PMID: 8344517; PMID: 1644304; PMID: 2077356; PMID:15365693; PMID: 7592377; spore pigment; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 
0.990
CBG73359.1
Putative biotin-dependent carboxylase.
 
  
 0.976
fabD
Malonyl CoA:acyl carrier protein malonyltransferase; PMID:7626609; PMID:15569690; PMID:7608065; PMID:8824610.
 
 
 0.919
sppH
Putative whiE protein II; PMID: 1644304; PMID:15365693; PMID: 8344517; PMID:12323376; spore pigment.
 
     0.913
CBG74921.1
Putative polyketide dehydratase component; PMID:8996103.
 
  
 0.912
sppD
Putative polyketide cyclase; PMID: 1644304; PMID: 2077356; PMID:12323376; spore pigment.
 
     0.894
sppC
Putative polyketide synthase acyl carrier protein; PMID: 2077356; PMID: 1644304; PMID: 8344517; PMID: 1527048; spore pigment.
  
 
 0.879
fabH-2
3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.863
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
  
 0.863
sppE
Putative polyketide synthesis cyclase; PMID: 2077356; PMID: 1644304; PMID: 7881555; spore pigment.
 
     0.851
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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