Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBG72322.1Putative MarR family transcriptional regulator; PMID:10099135. (168 aa)    
Predicted Functional Partners:
CBG72323.1
Putative oxidoreductase; PMID:7883183.
     
 0.796
mca
Conserved hypothetical protein; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
     0.606
CBG72988.1
Conserved hypothetical protein.
  
     0.583
CBG71285.1
Conserved hypothetical protein.
  
     0.573
mshD
Putative acetyltransferase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
     0.551
clpS
Putative ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
  
 0.543
CBG73609.1
Putative membrane protein.
       0.526
mshB
Putative N-acetylglucosaminylphosphatidylinositol de-N-acetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
     0.454
CBG75286.1
Putative MarR family transcriptional regulator.
  
     0.436
CBG75659.1
Putative MarR-family transcriptional regulator; PMID:15563836.
  
     0.431
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.