Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBG72346.1Putative secreted penicillin acylase. (948 aa)    
Predicted Functional Partners:
CBG71795.1
Putative peptidase family S45 (clan PB(S)); PMID:3680178.
  
  
 
0.928
CBG70954.1
Putative secreted beta-lactamase; TTA-Leu codon(s) 82 may indicate regulation by BldA.
     
  0.900
CBG72345.1
Putative Na+/H+ antiporter.
       0.735
CBG72344.1
Putative major facilitator transporter; Cluster 0562 with SCAB24121.
       0.645
CBG72343.1
Conserved hypothetical protein.
       0.622
CBG72342.1
Putative methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage.
       0.599
CBG71460.1
Putative polyketide synthase; PMID:14652074; PMID:10767533; many ~30% similar.
 
  
 0.506
vgb
Conserved hypothetical protein; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid.
      
 0.489
CBG71091.1
Conserved hypothetical protein.
  
     0.412
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (14%) [HD]