STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBG72417.1Conserved hypothetical protein; Doubtful CDS. (641 aa)    
Predicted Functional Partners:
CBG69551.1
GyrB-like gyrase subunit.
   
 
 0.730
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.730
snp3
Secreted extracellular small neutral protease.
  
    0.435
SCAB_5041
Conserved hypothetical protein; Cluster 0734 with SCAB82161.
  
     0.432
CBG69286.1
Putative secondary metabolite protein; PMID: 12642677; PMID: 16506694; PMID: 15827636.
  
     0.428
SCAB_5031
Putative methyltransferase; PMID:15686551; PMID:12940979.
  
   0.424
rarC3
RarC (conservon) homolog; PMID:12657469; conservon.
 
  
 0.422
CBG69285.1
Putative secondary metabolite protein; PMID: 15303497.
  
     0.402
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.