Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBG72514.1Putative two-component system histidine kinase. (422 aa)    
Predicted Functional Partners:
CBG72513.1
Putative two-component system reponse regulator.
 
   0.903
CBG69622.1
Putative sensory histidine kinase.
   
 
 0.875
SCAB_0821
Conserved hypothetical protein; PAS domain may indicate role in signal detection.
  
 
 0.805
CBG75927.1
Putative two-component sensor kinase.
 
 
 0.785
CBG73171.1
Putative sensor kinase.
   
 
 0.748
CBG73874.1
Putative two-component system response regulator.
 
 
 0.645
CBG70081.1
Putative two-component system response regulator.
 
   0.593
cya
Adenylate cyclase; PMID: 10376832.
 
 
 
 0.585
afsQ1
Two component system response regulator; PMID: 1339426.
 
   0.580
CBG72558.1
Putative two-component system response regulator.
 
   0.576
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.