Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
crtYPutative lycopene cyclase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster. (411 aa)    
Predicted Functional Partners:
crtI
Putative phytoene dehydrogenase (phytoene desaturase) (putative secreted protein); PMID:8917308; PMID:15716454; carotenoid pigment gene cluster.
 
 
 0.995
crtU
Putative dehydrogenase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster.
 
  
 0.993
crtB-1
Putative phytoene synthase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster.
 
  
 0.892
crtT
Putative methyltransferase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster.
 
   
 0.813
crtE
Putative geranylgeranyl pyrophosphate synthase; PMID:8917308; PMID:15716454; carotenoid pigment gene cluster; Belongs to the FPP/GGPP synthase family.
 
 
 0.804
crtV
Putative iron-sulfur protein; PMID:10767533; PMID:11200234; PMID:15716454; carotenoid pigment gene cluster.
 
  
 0.671
CBG73779.1
Putative secreted protein.
 
  
 0.577
CBG75220.1
Putative electron transfer flavoprotein, beta subunit.
  
 
 0.568
litS
Putative sigma factor; PMID:15716454; cluster 0758 with SCAB85121; carotenoid pigment gene cluster; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.502
hopD
Putative squalene/phytoene synthase.
  
  
 0.486
Your Current Organism:
Streptomyces scabiei
NCBI taxonomy Id: 680198
Other names: S. scabiei 87.22, Streptomyces scabiei 87.22, Streptomyces scabiei str. 87.22, Streptomyces scabiei strain 87.22
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.