STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHXM_04951Unannotated protein. (301 aa)    
Predicted Functional Partners:
purH
Unannotated protein.
       0.696
purN
Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.696
gyrB
Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.656
SHXM_07335
Unannotated protein.
    
 
 0.656
SHXM_06802
Unannotated protein.
    
   0.551
GCA_001553435_07429
Unannotated protein.
    
   0.551
SHXM_01336
Unannotated protein.
    
   0.431
SHXM_06544
Unannotated protein.
    
   0.431
SHXM_06545
Unannotated protein.
    
   0.431
Your Current Organism:
Streptomyces hygroscopicus
NCBI taxonomy Id: 68042
Other names: S. hygroscopicus subsp. hygroscopicus, Streptomyces hygroscopicus subsp. hygroscopicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.