STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHXM_00116Unannotated protein. (125 aa)    
Predicted Functional Partners:
SHXM_02882
Unannotated protein.
    
 0.849
SHXM_08406
Unannotated protein.
  
 0.755
SHXM_06035
Unannotated protein.
     
 0.746
icmF
Unannotated protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
  
 
 0.733
GCA_001553435_06652
Unannotated protein.
  
 
 0.700
GCA_001553435_08309
Unannotated protein.
  
 
 0.700
SHXM_01430
Unannotated protein.
    
 0.674
SHXM_01431
Unannotated protein.
    
 0.674
SHXM_07080
Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
  0.658
nuoI
Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 
 0.650
Your Current Organism:
Streptomyces hygroscopicus
NCBI taxonomy Id: 68042
Other names: S. hygroscopicus subsp. hygroscopicus, Streptomyces hygroscopicus subsp. hygroscopicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.