node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADL11118.1 | ADL11120.1 | CpC231_1656 | CpC231_1658 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Metal-dependent hydrolase. | 0.782 |
ADL11118.1 | ADL11122.1 | CpC231_1656 | CpC231_1660 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Rhomboid family protein. | 0.610 |
ADL11118.1 | ADL11123.1 | CpC231_1656 | CpC231_1661 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein. | 0.541 |
ADL11118.1 | murD-2 | CpC231_1656 | CpC231_1392 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.416 |
ADL11118.1 | murI | CpC231_1656 | CpC231_1659 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.971 |
ADL11118.1 | rph | CpC231_1656 | CpC231_1657 | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.992 |
ADL11120.1 | ADL11118.1 | CpC231_1658 | CpC231_1656 | Metal-dependent hydrolase. | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.782 |
ADL11120.1 | ADL11122.1 | CpC231_1658 | CpC231_1660 | Metal-dependent hydrolase. | Rhomboid family protein. | 0.643 |
ADL11120.1 | ADL11123.1 | CpC231_1658 | CpC231_1661 | Metal-dependent hydrolase. | Hypothetical protein. | 0.562 |
ADL11120.1 | murI | CpC231_1658 | CpC231_1659 | Metal-dependent hydrolase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.750 |
ADL11120.1 | rph | CpC231_1658 | CpC231_1657 | Metal-dependent hydrolase. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.833 |
ADL11122.1 | ADL11118.1 | CpC231_1660 | CpC231_1656 | Rhomboid family protein. | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.610 |
ADL11122.1 | ADL11120.1 | CpC231_1660 | CpC231_1658 | Rhomboid family protein. | Metal-dependent hydrolase. | 0.643 |
ADL11122.1 | ADL11123.1 | CpC231_1660 | CpC231_1661 | Rhomboid family protein. | Hypothetical protein. | 0.758 |
ADL11122.1 | murI | CpC231_1660 | CpC231_1659 | Rhomboid family protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.772 |
ADL11122.1 | rph | CpC231_1660 | CpC231_1657 | Rhomboid family protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.614 |
ADL11123.1 | ADL11118.1 | CpC231_1661 | CpC231_1656 | Hypothetical protein. | Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.541 |
ADL11123.1 | ADL11120.1 | CpC231_1661 | CpC231_1658 | Hypothetical protein. | Metal-dependent hydrolase. | 0.562 |
ADL11123.1 | ADL11122.1 | CpC231_1661 | CpC231_1660 | Hypothetical protein. | Rhomboid family protein. | 0.758 |
ADL11123.1 | murI | CpC231_1661 | CpC231_1659 | Hypothetical protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.601 |