STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000974445_08026Unannotated protein. (88 aa)    
Predicted Functional Partners:
UK23_00305
Unannotated protein.
 
 0.997
GCA_000974445_05414
Unannotated protein.
 
 0.979
ilvC
Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.973
leuB
Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
  
 0.969
UK23_25390
Unannotated protein; Belongs to the TPP enzyme family.
  
 0.969
UK23_07630
Unannotated protein.
 
 0.965
UK23_23240
Unannotated protein; Belongs to the TPP enzyme family.
 
 0.956
UK23_26730
Unannotated protein; Belongs to the TPP enzyme family.
 
 0.954
UK23_27750
Unannotated protein; Belongs to the TPP enzyme family.
  
 0.941
UK23_04780
Unannotated protein; Belongs to the TPP enzyme family.
  
 0.941
Your Current Organism:
Lentzea aerocolonigenes
NCBI taxonomy Id: 68170
Other names: ATCC 23870, BCRC 13661, CCRC 13661, CCRC:13661, CIP 107109, DSM 40034, IFO 13195, ISP 5034, JCM 4150, JCM 4614, L. aerocolonigenes, Lechevalieria aerocolonigenes, NBRC 13195, NRRL B-3298, NRRL ISP-5034, Nocardia aerocolonigenes, Saccharothrix aerocolonigenes, Streptomyces aerocolonigenes, strain Shinobu N 701
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.