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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANP56367.1Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)    
Predicted Functional Partners:
ANP49566.1
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.876
ANP49568.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
   
 
 0.789
ANP49567.1
AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.778
ANP56368.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.749
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 0.500
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.487
rpsC
30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
 0.479
ANP53791.1
Mannose-1-phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.472
rpsQ
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.471
rplN
50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
   0.468
Your Current Organism:
Streptomyces griseochromogenes
NCBI taxonomy Id: 68214
Other names: ATCC 14511, BCRC 11818, CBS 714.72, CCRC 11818, CCRC:11818, DSM 40499, IFO 13413, ISP 5499, JCM 4039, JCM 4764, KCTC 9027, NBRC 13413, NRRL B-12423, NRRL-ISP 5499, S. griseochromogenes, Streptomyces griseichromogenes
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