STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_002028425_02876Unannotated protein. (458 aa)    
Predicted Functional Partners:
GCA_002028425_02877
Unannotated protein.
       0.838
VR44_12860
Unannotated protein.
       0.838
VR44_12855
Unannotated protein.
      
0.816
gyrB
Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.572
VR44_18975
Unannotated protein.
    
 
 0.572
hutI
Unannotated protein; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
       0.497
VR44_12845
Unannotated protein.
       0.425
VR44_12840
Unannotated protein.
       0.425
Your Current Organism:
Streptomyces katrae
NCBI taxonomy Id: 68223
Other names: ATCC 27440, CBS 748.72, DSM 40550, IFO 13447, IMET 43361, ISP 5550, JCM 4777, NBRC 13447, NRRL B-3093, NRRL-ISP 5550, RIA 794, S. katrae, Streptomyces katrensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.