STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_002028425_05683Unannotated protein. (193 aa)    
Predicted Functional Partners:
GCA_002028425_06781
Unannotated protein.
  
     0.766
VR44_21785
Unannotated protein; Belongs to the ClpA/ClpB family.
  
 
 0.659
clpB
Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.659
VR44_06110
Unannotated protein.
  
 
 0.659
VR44_23215
Unannotated protein.
  
 
 0.659
VR44_35830
Unannotated protein.
  
 
 0.624
grpE
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]
  
  
 0.576
GCA_002028425_05682
Unannotated protein.
       0.574
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.561
GCA_002028425_05690
Unannotated protein.
  
 
 0.561
Your Current Organism:
Streptomyces katrae
NCBI taxonomy Id: 68223
Other names: ATCC 27440, CBS 748.72, DSM 40550, IFO 13447, IMET 43361, ISP 5550, JCM 4777, NBRC 13447, NRRL B-3093, NRRL-ISP 5550, RIA 794, S. katrae, Streptomyces katrensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.