STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000745715_06312Unannotated protein. (225 aa)    
Predicted Functional Partners:
gyrB
Unannotated protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.963
GCA_000745715_07480
Unannotated protein.
    
 
 0.963
GCA_000745715_06313
Unannotated protein.
       0.780
GCA_000745715_06314
Unannotated protein.
       0.726
GCA_000745715_00515
Unannotated protein.
  
  
 0.491
GCA_000745715_00829
Unannotated protein.
  
  
 0.491
GCA_000745715_01101
Unannotated protein.
  
  
 0.491
GCA_000745715_01506
Unannotated protein.
  
  
 0.491
GCA_000745715_01943
Unannotated protein.
  
  
 0.491
GCA_000745715_04043
Unannotated protein.
  
  
 0.491
Your Current Organism:
Streptomyces mirabilis
NCBI taxonomy Id: 68239
Other names: ATCC 27447, Actinomyces mirabilis, CBS 751.72, DSM 40553, IFO 13450, ISP 5553, JCM 4551, JCM 4791, NBRC 13450, NRRL B-2400, NRRL-ISP 5553, S. mirabilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.