STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000745715_09045Unannotated protein. (289 aa)    
Predicted Functional Partners:
disA
Unannotated protein; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
  
 0.899
recX
Unannotated protein; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.885
recA
Unannotated protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
  
 0.882
GCA_000745715_04410
Unannotated protein; Belongs to the helicase family. UvrD subfamily.
 
  
 0.877
thiL
Unannotated protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
   
    0.842
GCA_000745715_09046
Unannotated protein.
       0.778
GCA_000745715_09044
Unannotated protein.
       0.698
GCA_000745715_04654
Unannotated protein.
  
     0.687
GCA_000745715_07541
Unannotated protein.
  
   
 0.682
GCA_000745715_04588
Unannotated protein.
  
     0.652
Your Current Organism:
Streptomyces mirabilis
NCBI taxonomy Id: 68239
Other names: ATCC 27447, Actinomyces mirabilis, CBS 751.72, DSM 40553, IFO 13450, ISP 5553, JCM 4551, JCM 4791, NBRC 13450, NRRL B-2400, NRRL-ISP 5553, S. mirabilis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.