close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOW85351.1Sulfatase modifying factor 1 (C-alpha-formyglycine- generating enzyme 1); Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)    
Predicted Functional Partners:
AOW90928.1
Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.999
BC342_12480
Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.912
egtD
Dimethylhistidine N-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
 
 
 0.900
AOW89888.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.885
egtC
Ergothioneine biosynthesis protein EgtC; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.
  
 
  0.722
AOW85354.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.714
AOW85353.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.627
AOW91103.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.593
AOW89843.1
Beta-amylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
AOW85352.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.562
Your Current Organism:
Streptomyces pactum
NCBI taxonomy Id: 68249
Other names: ATCC 27456, BCRC 12076, CBS 461.69, CBS 734.72, CCRC 12076, CCRC:12076, DSM 40530, IFO 13433, IMET 43357, ISP 5530, JCM 4288, JCM 4809, KCTC 9165, LMG 19357, LMG:19357, NBRC 13433, NCIMB 9445, NRRL 2939, NRRL ISP-5530, NRRL-ISP 5530, S. pactum, Streptomyces pactum var. pactum, Streptomyces pactus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.