STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOW87713.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)    
Predicted Functional Partners:
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
    
 0.867
AOW87714.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.847
AOW88942.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.841
AOW87868.1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.838
AOW86583.1
Signal protein PDZ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.827
AOW87712.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.816
AOW87715.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.768
AOW91523.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.759
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
    
 0.759
BC342_15440
Hydrolase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.751
Your Current Organism:
Streptomyces pactum
NCBI taxonomy Id: 68249
Other names: ATCC 27456, BCRC 12076, CBS 461.69, CBS 734.72, CCRC 12076, CCRC:12076, DSM 40530, IFO 13433, IMET 43357, ISP 5530, JCM 4288, JCM 4809, KCTC 9165, LMG 19357, LMG:19357, NBRC 13433, NCIMB 9445, NRRL 2939, NRRL ISP-5530, NRRL-ISP 5530, S. pactum, Streptomyces pactum var. pactum, Streptomyces pactus
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