Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOW91251.1Anion-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)    
Predicted Functional Partners:
AOW88186.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.788
BC342_19745
NAD-dependent dehydratase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.731
pyrF
Orotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
   0.728
AOW86549.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.726
AOW87252.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.723
AOW91253.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.715
AOW87685.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
AOW87688.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.654
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
   0.641
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
   0.636
Your Current Organism:
Streptomyces pactum
NCBI taxonomy Id: 68249
Other names: ATCC 27456, BCRC 12076, CBS 461.69, CBS 734.72, CCRC 12076, CCRC:12076, DSM 40530, IFO 13433, IMET 43357, ISP 5530, JCM 4288, JCM 4809, KCTC 9165, LMG 19357, LMG:19357, NBRC 13433, NCIMB 9445, NRRL 2939, NRRL ISP-5530, NRRL-ISP 5530, S. pactum, Streptomyces pactum var. pactum, Streptomyces pactus
Server load: low (24%) [HD]