STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEU35401.12-oxoglutarate dehydrogenase, E1 subunit; SMART: Transketolase-like, pyrimidine-binding domain; TIGRFAM: 2-oxoglutarate dehydrogenase, E1 component; KEGG: aca:ACP_0050 2-oxoglutarate dehydrogenase E1 component; PFAM: Transketolase-like, pyrimidine-binding domain; Dehydrogenase, E1 component. (839 aa)    
Predicted Functional Partners:
AEU39122.1
TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component; KEGG: aca:ACP_2354 putative dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
 0.999
AEU39120.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: aca:ACP_2857 dihydrolipoyl dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 
 0.983
AEU35629.1
TIGRFAM: Isocitrate dehydrogenase NADP-dependent, prokaryotic; KEGG: aca:ACP_0089 isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase.
   
 
 0.966
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.960
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.942
AEU36277.1
PFAM: Forkhead-associated (FHA) domain; KEGG: ssm:Spirs_0096 FHA domain containing protein.
    
 
 0.918
AEU37975.1
KEGG: aca:ACP_1462 putative isocitrate dehydrogenase, NAD-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase.
  
 0.916
AEU35645.1
TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; KEGG: aba:Acid345_2571 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal.
 
 
 0.873
AEU35152.1
PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; KEGG: aca:ACP_2883 glutamate dehydrogenase; SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.854
AEU35642.1
KEGG: aba:Acid345_2572 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein.
  
 
 0.842
Your Current Organism:
Granulicella mallensis
NCBI taxonomy Id: 682795
Other names: G. mallensis MP5ACTX8, Granulicella mallensis MP5ACTX8, Granulicella mallensis str. MP5ACTX8, Granulicella mallensis strain MP5ACTX8, Granulicella sp. MP5ACTX8
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