node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEU34722.1 | AEU34865.1 | AciX8_0367 | AciX8_0514 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.834 |
AEU34722.1 | AEU35962.1 | AciX8_0367 | AciX8_1623 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; manually curated; KEGG: aca:ACP_3488 lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; Belongs to the LpxB family. | 0.960 |
AEU34722.1 | AEU38201.1 | AciX8_0367 | AciX8_3918 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; KEGG: aca:ACP_1676 sugar isomerase, KpsF/GutQ family; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core. | 0.845 |
AEU34722.1 | AEU38873.1 | AciX8_0367 | AciX8_4603 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; KEGG: aca:ACP_2344 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. | 0.789 |
AEU34722.1 | kdsB | AciX8_0367 | AciX8_2108 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.821 |
AEU34722.1 | lpxC | AciX8_0367 | AciX8_0040 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.983 |
AEU34722.1 | lpxK | AciX8_0367 | AciX8_0515 | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.838 |
AEU34865.1 | AEU34722.1 | AciX8_0514 | AciX8_0367 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.834 |
AEU34865.1 | AEU35962.1 | AciX8_0514 | AciX8_1623 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; manually curated; KEGG: aca:ACP_3488 lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; Belongs to the LpxB family. | 0.835 |
AEU34865.1 | AEU36672.1 | AciX8_0514 | AciX8_2355 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; KEGG: aca:ACP_2430 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; PFAM: HAD superfamily hydrolase-like, type 3. | 0.631 |
AEU34865.1 | AEU37628.1 | AciX8_0514 | AciX8_3330 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Haloacid dehalogenase domain protein hydrolase type 3; PFAM: HAD superfamily hydrolase-like, type 3; KEGG: sus:Acid_2245 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. | 0.561 |
AEU34865.1 | AEU38201.1 | AciX8_0514 | AciX8_3918 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ; KEGG: aca:ACP_1676 sugar isomerase, KpsF/GutQ family; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core. | 0.857 |
AEU34865.1 | AEU38606.1 | AciX8_0514 | AciX8_4333 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; KEGG: aba:Acid345_3769 phosphatase KdsC; PFAM: HAD superfamily hydrolase-like, type 3. | 0.607 |
AEU34865.1 | AEU38873.1 | AciX8_0514 | AciX8_4603 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; KEGG: aca:ACP_2344 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA. | 0.824 |
AEU34865.1 | kdsB | AciX8_0514 | AciX8_2108 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.982 |
AEU34865.1 | lpxC | AciX8_0514 | AciX8_0040 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.835 |
AEU34865.1 | lpxK | AciX8_0514 | AciX8_0515 | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.999 |
AEU35962.1 | AEU34722.1 | AciX8_1623 | AciX8_0367 | lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; manually curated; KEGG: aca:ACP_3488 lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; Belongs to the LpxB family. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.960 |
AEU35962.1 | AEU34865.1 | AciX8_1623 | AciX8_0514 | lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; manually curated; KEGG: aca:ACP_3488 lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; Belongs to the LpxB family. | Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.835 |
AEU35962.1 | AEU36672.1 | AciX8_1623 | AciX8_2355 | lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; manually curated; KEGG: aca:ACP_3488 lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; Belongs to the LpxB family. | TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; KEGG: aca:ACP_2430 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; PFAM: HAD superfamily hydrolase-like, type 3. | 0.487 |