STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEU38561.18-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (406 aa)    
Predicted Functional Partners:
AEU38558.1
KEGG: aba:Acid345_3920 L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal.
 
 
 0.962
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.916
gcvPB
Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
  
 
 0.914
gcvPA
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
  
 
 0.913
AEU36928.1
Glycine C-acetyltransferase; KEGG: eat:EAT1b_0424 pyridoxal phosphate-dependent acyltransferase; PFAM: Aminotransferase, class I/classII.
  
  
 
0.911
AEU35971.1
KEGG: aca:ACP_0847 threonine aldolase, low-specificity; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase.
   
 
 0.908
AEU36657.1
Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
   
 
 0.908
AEU35172.1
Serine 3-dehydrogenase; KEGG: aca:ACP_1478 oxidoreductase, short chain dehydrogenase/reductase family; PFAM: Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
  0.901
AEU37572.1
Long-chain-fatty-acid--CoA ligase., 6-deoxyerythronolide-B synthase; PFAM: AMP-dependent synthetase/ligase; Polyketide synthase, KR; Beta-ketoacyl synthase, C-terminal; Beta-ketoacyl synthase, N-terminal; Phosphopantetheine-binding; KEGG: bam:Bamb_6478 beta-ketoacyl synthase; SMART: Polyketide synthase, beta-ketoacyl synthase domain; Polyketide synthase, phosphopantetheine-binding; Polyketide synthase/Fatty acid synthase, KR.
 
 
 0.758
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.688
Your Current Organism:
Granulicella mallensis
NCBI taxonomy Id: 682795
Other names: G. mallensis MP5ACTX8, Granulicella mallensis MP5ACTX8, Granulicella mallensis str. MP5ACTX8, Granulicella mallensis strain MP5ACTX8, Granulicella sp. MP5ACTX8
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