STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rsmGHypothetical protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (188 aa)    
Predicted Functional Partners:
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
  
 0.927
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
  
  
 0.917
EFC31950.1
Chromosome partitioning protein, ParB family; C414_000440003 identified by Glimmer3 with a raw score of 12.56. Gene function extrapolated from JJD26997_0108 (CP000768.1) after blastn alignment (95.36 percent identity over a 646 bp alignment); Belongs to the ParB family.
  
  
 0.743
EFC32670.1
Hypothetical protein; C414_000230016 identified by Glimmer3 with a raw score of 13.24. Gene function extrapolated from JJD26997_0824 (CP000768.1) after blastn alignment (96.36 percent identity over a 110 bp alignment) - for clarity, the original product name 'conserved hypothetical protein' has been renamed.
  
  
 0.686
EFC32701.1
GTP cyclohydrolase II; C414_000230047 identified by Glimmer3 with a raw score of 10.44. Gene function extrapolated from JJD26997_0793 (CP000768.1) after blastn alignment (92.86 percent identity over a 504 bp alignment).
       0.674
yidC
Inner membrane protein, 60 kDa; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
  
 0.606
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.569
rlmH
Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
 
   
 0.569
rsmI
Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.562
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.557
Your Current Organism:
Campylobacter jejuni 414
NCBI taxonomy Id: 683083
Other names: C. jejuni subsp. jejuni 414, Campylobacter jejuni subsp. jejuni 414, Campylobacter jejuni subsp. jejuni str. 414, Campylobacter jejuni subsp. jejuni strain 414
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.