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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFC32098.1Fumarate reductase, cytochrome b subunit; C414_000420030 identified by Glimmer3 with a raw score of 8.42. Gene function extrapolated from JJD26997_1549 (CP000768.1) after blastn alignment (95.93 percent identity over a 589 bp alignment). (258 aa)    
Predicted Functional Partners:
FrdB
Fumarate reductase, iron-sulfur protein subunit; C414_000420028 identified by Glimmer3 with a raw score of 12.99. Gene function extrapolated from CJJ81176_0434 (CP000538.1) after blastn alignment (95.59 percent identity over a 726 bp alignment); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 
 0.999
EFC32097.1
Fumarate reductase, flavoprotein subunit; C414_000420029 identified by Glimmer3 with a raw score of 10.89. Gene function extrapolated from JJD26997_1548 (CP000768.1) after blastn alignment (93.98 percent identity over a 1992 bp alignment).
 
 0.999
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.989
EFC32214.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; C414_000390037 identified by Glimmer3 with a raw score of 8.99. Gene function extrapolated from CJJ81176_1469 (CP000538.1) after blastn alignment (93.71 percent identity over a 3561 bp alignment).
   
  
 0.984
sucD
succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.982
EFC32073.1
Hypothetical protein; C414_000420005 identified by Glimmer3 with a raw score of 14.32. A blastn search against coding sequences extracted from AL111168.1, CP000025.1, CP000538.1, CP000768.1, CP000814.1 failed to identify a similar sequence, and so no function could be assigned.
  
 0.981
EFC32197.1
Hypothetical protein; Features C414_000390019, C414_000390020 joined to form C414_000390044 to correct 454 sequencing error (C414_000390019 identified by Glimmer3 with a raw score of 13.94, C414_000390020 identified by Glimmer3 with a raw score of 12.54). Gene function extrapolated from Cj1459 (AL111168.1) after blastn alignment (96.70 percent identity over a 91 bp alignment). Similar to Cj1459.
  
 0.980
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 
 0.965
nuoD
NADH dehydrogenase I chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
   
 
 0.878
EFC32337.1
Ubiquinol--cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
  
 0.849
Your Current Organism:
Campylobacter jejuni 414
NCBI taxonomy Id: 683083
Other names: C. jejuni subsp. jejuni 414, Campylobacter jejuni subsp. jejuni 414, Campylobacter jejuni subsp. jejuni str. 414, Campylobacter jejuni subsp. jejuni strain 414
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