node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fen1 | TCAL_00424 | A0A553PAQ7 | A0A553NC59 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | TPR_REGION domain-containing protein. | 0.886 |
Fen1 | TCAL_01790 | A0A553PAQ7 | A0A553N7H5 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.890 |
Fen1 | TCAL_01841 | A0A553PAQ7 | A0A553ND66 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.918 |
Fen1 | TCAL_01883 | A0A553PAQ7 | A0A553P7K4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ERCC4 domain-containing protein. | 0.880 |
Fen1 | TCAL_03979 | A0A553PAQ7 | A0A553ND28 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.999 |
Fen1 | TCAL_04131 | A0A553PAQ7 | A0A553NTU6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.583 |
Fen1 | TCAL_04459 | A0A553PAQ7 | A0A553NZM1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. | 0.932 |
Fen1 | TCAL_08684 | A0A553PAQ7 | A0A553NB60 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Uncharacterized protein. | 0.542 |
Fen1 | TCAL_11816 | A0A553PAQ7 | A0A553N7V2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RECA_2 domain-containing protein. | 0.861 |
Fen1 | TCAL_13535 | A0A553PAQ7 | A0A553N8B0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RECA_2 domain-containing protein. | 0.787 |
TCAL_00424 | Fen1 | A0A553NC59 | A0A553PAQ7 | TPR_REGION domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.886 |
TCAL_00424 | TCAL_01790 | A0A553NC59 | A0A553N7H5 | TPR_REGION domain-containing protein. | Uncharacterized protein. | 0.892 |
TCAL_00424 | TCAL_01841 | A0A553NC59 | A0A553ND66 | TPR_REGION domain-containing protein. | Uncharacterized protein. | 0.898 |
TCAL_00424 | TCAL_01883 | A0A553NC59 | A0A553P7K4 | TPR_REGION domain-containing protein. | ERCC4 domain-containing protein. | 0.919 |
TCAL_00424 | TCAL_03979 | A0A553NC59 | A0A553ND28 | TPR_REGION domain-containing protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.998 |
TCAL_00424 | TCAL_04131 | A0A553NC59 | A0A553NTU6 | TPR_REGION domain-containing protein. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.705 |
TCAL_00424 | TCAL_04459 | A0A553NC59 | A0A553NZM1 | TPR_REGION domain-containing protein. | DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. | 0.984 |
TCAL_00424 | TCAL_08684 | A0A553NC59 | A0A553NB60 | TPR_REGION domain-containing protein. | Uncharacterized protein. | 0.736 |
TCAL_00424 | TCAL_11816 | A0A553NC59 | A0A553N7V2 | TPR_REGION domain-containing protein. | RECA_2 domain-containing protein. | 0.886 |
TCAL_00424 | TCAL_13535 | A0A553NC59 | A0A553N8B0 | TPR_REGION domain-containing protein. | RECA_2 domain-containing protein. | 0.917 |