STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCAL_09653ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (632 aa)    
Predicted Functional Partners:
TCAL_08807
Guanylate kinase-like domain-containing protein.
 
  
  0.745
TCAL_14881
Uncharacterized protein.
    
 0.675
TCAL_11816
RECA_2 domain-containing protein.
      
 0.658
TCAL_04638
Uncharacterized protein.
 
  
   0.638
TCAL_03979
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
  
 
0.627
TCAL_00424
TPR_REGION domain-containing protein.
    
 
 0.624
TCAL_09685
Glutamine amidotransferase type-2 domain-containing protein.
   
 
  0.584
TCAL_11256
Ku domain-containing protein.
    
 
 0.555
Fen1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
    
 
 0.548
TCAL_11508
Protein kinase domain-containing protein.
   
 
  0.544
Your Current Organism:
Tigriopus californicus
NCBI taxonomy Id: 6832
Other names: T. californicus, tidepool copepod
Server load: low (22%) [HD]