node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fen1 | TCAL_00424 | A0A553PAQ7 | A0A553NC59 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | TPR_REGION domain-containing protein. | 0.886 |
Fen1 | TCAL_03979 | A0A553PAQ7 | A0A553ND28 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.999 |
Fen1 | TCAL_09653 | A0A553PAQ7 | A0A553NSU0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.548 |
Fen1 | TCAL_11256 | A0A553PAQ7 | A0A553NE26 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Ku domain-containing protein. | 0.779 |
Fen1 | TCAL_11816 | A0A553PAQ7 | A0A553N7V2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | RECA_2 domain-containing protein. | 0.861 |
TCAL_00424 | Fen1 | A0A553NC59 | A0A553PAQ7 | TPR_REGION domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.886 |
TCAL_00424 | TCAL_03979 | A0A553NC59 | A0A553ND28 | TPR_REGION domain-containing protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.998 |
TCAL_00424 | TCAL_09653 | A0A553NC59 | A0A553NSU0 | TPR_REGION domain-containing protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.624 |
TCAL_00424 | TCAL_11256 | A0A553NC59 | A0A553NE26 | TPR_REGION domain-containing protein. | Ku domain-containing protein. | 0.903 |
TCAL_00424 | TCAL_11816 | A0A553NC59 | A0A553N7V2 | TPR_REGION domain-containing protein. | RECA_2 domain-containing protein. | 0.886 |
TCAL_03979 | Fen1 | A0A553ND28 | A0A553PAQ7 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.999 |
TCAL_03979 | TCAL_00424 | A0A553ND28 | A0A553NC59 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | TPR_REGION domain-containing protein. | 0.998 |
TCAL_03979 | TCAL_04638 | A0A553ND28 | A0A553ND35 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Uncharacterized protein. | 0.572 |
TCAL_03979 | TCAL_09653 | A0A553ND28 | A0A553NSU0 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.627 |
TCAL_03979 | TCAL_11256 | A0A553ND28 | A0A553NE26 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Ku domain-containing protein. | 0.996 |
TCAL_03979 | TCAL_11816 | A0A553ND28 | A0A553N7V2 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | RECA_2 domain-containing protein. | 0.993 |
TCAL_04638 | TCAL_03979 | A0A553ND35 | A0A553ND28 | Uncharacterized protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.572 |
TCAL_04638 | TCAL_09653 | A0A553ND35 | A0A553NSU0 | Uncharacterized protein. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.638 |
TCAL_04638 | TCAL_09685 | A0A553ND35 | A0A553NZ06 | Uncharacterized protein. | Glutamine amidotransferase type-2 domain-containing protein. | 0.584 |
TCAL_04638 | TCAL_14881 | A0A553ND35 | A0A553P1N3 | Uncharacterized protein. | Uncharacterized protein. | 0.429 |