STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCAL_033312-Hacid_dh_C domain-containing protein. (329 aa)    
Predicted Functional Partners:
TCAL_06969
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.845
TCAL_00721
Mitogen-activated protein kinase.
  
 
 0.834
TCAL_03277
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.823
TCAL_11779
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
   
 
 0.820
TCAL_03124
Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.814
TCAL_09253
SHMT domain-containing protein.
  
 0.813
TCAL_04503
SHMT domain-containing protein.
  
 0.813
TCAL_07977
Uncharacterized protein.
  
 0.775
TCAL_00529
FMN hydroxy acid dehydrogenase domain-containing protein.
    
 0.770
TCAL_07841
Uncharacterized protein.
    
 0.766
Your Current Organism:
Tigriopus californicus
NCBI taxonomy Id: 6832
Other names: T. californicus, tidepool copepod
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.