STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL50381.1Predicted oxidoreductase. (289 aa)    
Predicted Functional Partners:
SCL63289.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
    
 0.609
SCL50384.1
Proteasome lid subunit RPN8/RPN11, contains Jab1/MPN metalloenzyme (JAMM) motif.
   
   0.550
SCL46101.1
Glycerol uptake facilitator (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.495
SCL48608.1
Glycerol uptake facilitator (Major Intrinsic Protein Family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.495
SCL50319.1
Aquaporin Z; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.495
SCL49133.1
Hypothetical protein.
   
   0.493
SCL50253.1
2,5-diketo-D-gluconate reductase A.
 
0.483
SCL55757.1
D-threo-aldose 1-dehydrogenase.
  
     0.482
SCL50347.1
Aldo/keto reductase.
 
0.470
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
    
   0.455
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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