STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (368 aa)    
Predicted Functional Partners:
SCL52148.1
Oxygen-dependent protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.992
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.981
SCL63243.1
uroporphyrinogen-III synthase.
 
 
 0.955
SCL61591.1
uroporphyrinogen-III C-methyltransferase.
    
 0.948
SCL59368.1
Glutamate synthase (NADH) large subunit.
 
  
 0.946
SCL63877.1
uroporphyrinogen-III C-methyltransferase.
  
 
 0.944
SCL60017.1
UDP-galactopyranose mutase.
  
 
 0.900
SCL55602.1
Oxygen-independent coproporphyrinogen-3 oxidase.
  
 
 0.886
SCL52151.1
Chlorite dismutase.
 
  
 0.864
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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