STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCL59966.12-oxoglutarate dehydrogenase E2 component. (610 aa)    
Predicted Functional Partners:
SCL54895.1
Pyruvate dehydrogenase E1 component beta subunit.
 
 0.999
SCL54899.1
Pyruvate dehydrogenase E1 component alpha subunit.
 
 0.999
SCL59963.1
Dihydrolipoamide dehydrogenase.
 0.999
SCL60327.1
2-oxoisovalerate dehydrogenase E1 component.
 
 0.999
SCL60808.1
2-oxoisovalerate dehydrogenase E1 component.
 
 0.998
SCL62402.1
2-oxoglutarate dehydrogenase E1 component.
 
0.998
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.989
SCL46451.1
Pyruvate dehydrogenase E1 component alpha subunit.
 
 0.987
SCL56532.1
Pyruvate dehydrogenase E1 component alpha subunit.
 
 0.987
SCL60342.1
Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.987
Your Current Organism:
Micromonospora yangpuensis
NCBI taxonomy Id: 683228
Other names: CGMCC 4.5736, DSM 45577, M. yangpuensis, Micromonospora sp. FXJ6.011, Micromonospora yangpuensis Zhang et al. 2012, NBRC 107727, strain FXJ6.011
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