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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein.
 
 0.999
DC74_3665
Putative fructose-specific permease.
 
  
 0.996
DC74_1677
Phosphoenolpyruvate-dependent sugar phosphotransferase.
 
 
 0.992
DC74_560
Dihydroxyacetone kinase, phosphotransfer subunit.
 
 
 0.978
DC74_591
Phosphoenolpyruvate synthase.
    
 0.905
DC74_3666
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.870
DC74_4790
PTS sucrose-specific enzyme IIBC component.
 
  
 0.848
DC74_4773
Sugar kinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.841
DC74_3339
Phosphotransferase system IIB component.
 
  
 0.740
DC74_3341
Phosphotransferase system IIC component.
  
 0.732
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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