STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DC74_1920Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (762 aa)    
Predicted Functional Partners:
DC74_3865
2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.991
DC74_6048
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.964
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.960
DC74_3866
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.942
DC74_5432
Alpha-ketoglutarate decarboxylase.
   
 
 0.939
DC74_2507
Glutamate synthase(NADPH) large subunit.
     
 0.919
DC74_5613
gdhA; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.855
DC74_4858
Citrate synthase 2; Belongs to the citrate synthase family.
  
  
 0.853
DC74_4588
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.839
DC74_6655
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.828
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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