Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
DC74_2118Ferredoxin. (97 aa)    
Predicted Functional Partners:
arc
Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
 
     0.768
DC74_2116
Proteasome component.
 
     0.714
mqnA
Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
     0.702
pup
Hypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.
 
     0.698
prcA
20S proteasome alpha-subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
 
     0.656
prcB
20S proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
 
     0.656
DC74_2276
Hypothetical protein.
  
     0.608
mqnB
Hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
     0.592
DC74_3970
Hypothetical protein.
  
     0.587
DC74_2718
Hypothetical protein.
  
     0.572
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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