Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DC74_2302Two-component system response regulator. (227 aa)    
Predicted Functional Partners:
DC74_2303
Hypothetical protein.
 
 
 0.976
DC74_1817
Hypothetical protein.
 
   0.783
DC74_5751
Hypothetical protein.
 
   0.762
DC74_8090
Putative two-component system sensor kinase.
 
 
 0.751
DC74_5832
Two-component system sensor kinase.
  
 
 0.748
DC74_5910
Two-component system sensor kinase.
 
   0.742
DC74_7616
Nitrate/nitrite sensor protein.
 
   0.741
DC74_2301
Putative chaplin.
       0.735
DC74_7136
Two component system sensor kinase.
 
   0.719
DC74_2661
Hypothetical protein.
 
   0.715
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
Server load: low (12%) [HD]