STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DC74_2802Oxidoreductase; Belongs to the aldehyde dehydrogenase family. (483 aa)    
Predicted Functional Partners:
DC74_1191
AMP-dependent synthetase and ligase.
  
 0.929
acsA_2
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.929
DC74_5775
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.926
DC74_6457
Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.926
DC74_3210
Methylmalonic acid semialdehyde dehydrogenase.
  
  
 
0.921
DC74_400
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.920
DC74_5986
Methylmalonic acid semialdehyde dehydrogenase MmsA.
  
  
 
0.920
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.918
DC74_6742
Fatty acid oxidation complex alpha-subunit.
  
 0.917
DC74_6871
Bifunctional P-450:NADPH-P450 reductase 1.
   
 0.915
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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