era protein (Streptomyces albulus) - STRING interaction network

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era

GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (312 aa)

Predicted Functional Partners:

DC74_3066

0.967

ybeY

0.918

rpsP

0.881

rspG

0.867

rpsF

0.865

rpsI

0.863

rpsJ

0.845

rpsE

0.829

rsmA

0.826

rpsB

0.809

Your Current Organism:

Streptomyces albulus

NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DC74_3066	era	DC74_3066	DC74_3065	Hypothetical protein.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.967
DC74_3066	ybeY	DC74_3066	DC74_3068	Hypothetical protein.	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.857
era	DC74_3066	DC74_3065	DC74_3066	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Hypothetical protein.	0.967
era	rpsB	DC74_3065	DC74_5741	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.809
era	rpsE	DC74_3065	DC74_3807	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.829
era	rpsF	DC74_3065	DC74_4236	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.865
era	rpsI	DC74_3065	DC74_3791	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.863
era	rpsJ	DC74_3065	DC74_3825	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.845
era	rpsP	DC74_3065	DC74_5724	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.881
era	rsmA	DC74_3065	DC74_3592	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.826
era	rspG	DC74_3065	DC74_3828	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.867
era	ybeY	DC74_3065	DC74_3068	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.	0.918
rpsB	era	DC74_5741	DC74_3065	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.	0.809
rpsB	rpsE	DC74_5741	DC74_3807	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.998
rpsB	rpsF	DC74_5741	DC74_4236	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.	0.996
rpsB	rpsI	DC74_5741	DC74_3791	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.998
rpsB	rpsJ	DC74_5741	DC74_3825	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.998
rpsB	rpsP	DC74_5741	DC74_5724	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.998
rpsB	rsmA	DC74_5741	DC74_3592	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.	0.875
rpsB	rspG	DC74_5741	DC74_3828	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999

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