Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DC74_37712-hydroxyacid family dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 
 
 0.757
DC74_3227
Hypothetical protein.
 
     0.700
DC74_3229
Oxidoreductase.
 
  
 0.697
DC74_3228
Hypothetical protein.
 
     0.677
DC74_2742
Solute-binding lipoprotein.
 
     0.636
DC74_2740
Integral membrane transporter.
 
     0.594
DC74_2741
ABC-type sugar transport system, permease component.
 
     0.593
DC74_3770
Putative dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.588
DC74_2140
Oxidoreductase.
 
 
   0.504
DC74_463
Oxidoreductase domain-containing protein.
 
  
 0.471
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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