Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DC74_4109Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (255 aa)    
Predicted Functional Partners:
DC74_4105
Bifunctional protein S-adenosyl-L-methionine-precorrin-2 methyl transferaseprecorrin-3 methylase.
 
 0.999
DC74_4110
precorrin-6Y C5,15-methyltransferase.
  
 0.998
DC74_2009
precorrin-6Y C5,15-methyltransferase.
  
 0.994
DC74_4106
precorrin-6X reductase.
 
  
 0.993
cobH
precorrin-8X methylmutase.
 
  
 0.991
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.987
cbiD
cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.970
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.950
DC74_4102
Cobalamin biosynthesis protein CobN.
 
  
 0.933
DC74_2666
Adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase.
 
  
 0.918
Your Current Organism:
Streptomyces albulus
NCBI taxonomy Id: 68570
Other names: ATCC 12757, BCRC 11819, CBS 711.72, CCRC 11819, CCRC:11819, DSM 40492, IFO 13410, ISP 5492, JCM 4718, KCTC 9668, NBRC 13410, NRRL B-5386, NRRL-ISP 5492, S. albulus, strain IMC S-0802
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